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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPR2
All Species:
35.15
Human Site:
S641
Identified Species:
70.3
UniProt:
P20594
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20594
NP_003986.2
1047
117022
S641
L
H
N
S
I
I
S
S
H
G
S
L
K
S
S
Chimpanzee
Pan troglodytes
XP_001168194
1047
116964
S641
L
H
N
S
I
I
S
S
H
G
S
L
K
S
S
Rhesus Macaque
Macaca mulatta
XP_001085221
1047
116990
S641
L
H
N
S
I
I
S
S
H
G
S
L
K
S
S
Dog
Lupus familis
XP_531993
999
112273
G616
V
L
K
I
T
D
Y
G
L
A
S
F
R
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6VVW5
1047
117039
S641
L
H
N
S
I
I
S
S
H
G
S
L
K
S
S
Rat
Rattus norvegicus
P16067
1047
117109
S641
L
H
N
S
I
I
S
S
H
G
S
L
K
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517544
743
84256
T395
L
C
P
G
R
L
P
T
M
G
M
Q
K
G
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084176
1082
122776
S677
L
H
R
S
I
I
G
S
H
G
N
L
K
S
S
Zebra Danio
Brachydanio rerio
XP_689479
1088
124806
S683
L
H
N
S
Y
I
G
S
H
G
N
L
K
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07553
1163
130896
S649
L
H
D
S
E
I
I
S
H
G
N
L
R
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09435
1137
128085
L681
L
H
K
T
F
L
R
L
H
G
N
L
R
S
A
Sea Urchin
Strong. purpuratus
P16065
1125
126238
S690
L
H
S
S
E
I
K
S
H
G
H
L
K
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.8
89.1
N.A.
98.5
98.5
N.A.
64.5
N.A.
72.2
58.1
N.A.
32.5
N.A.
28.7
36.2
Protein Similarity:
100
99.9
100
90
N.A.
99.4
99.3
N.A.
67
N.A.
82.9
69.7
N.A.
49
N.A.
46.7
52.2
P-Site Identity:
100
100
100
13.3
N.A.
100
100
N.A.
20
N.A.
80
80
N.A.
66.6
N.A.
40
73.3
P-Site Similarity:
100
100
100
33.3
N.A.
100
100
N.A.
33.3
N.A.
86.6
86.6
N.A.
86.6
N.A.
73.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
9
0
0
17
9
0
92
0
0
0
9
0
% G
% His:
0
84
0
0
0
0
0
0
84
0
9
0
0
0
0
% H
% Ile:
0
0
0
9
50
75
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
17
0
0
0
9
0
0
0
0
0
75
0
0
% K
% Leu:
92
9
0
0
0
17
0
9
9
0
0
84
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% M
% Asn:
0
0
50
0
0
0
0
0
0
0
34
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
0
0
9
0
9
0
9
0
0
0
0
0
25
0
0
% R
% Ser:
0
0
9
75
0
0
42
75
0
0
50
0
0
92
75
% S
% Thr:
0
0
0
9
9
0
0
9
0
0
0
0
0
0
9
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _